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Clinical characteristics and outcomes of biopsy-proven diabetic nephropathy

Li Zhuo, Nianrong Zhang, Guming Zou, Dapeng Chen, Wenge Li

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 386-392 doi: 10.1007/s11684-017-0574-z

Abstract: In this study, the clinical manifestations of 111 cases of biopsy-proven DN were described, and the clinicalHematuria (48.6%) failed to specify either DN or nondiabetic renal disease.Kaplan–Meier analysis revealed that the renal survival of 53 patients who were diagnosed with DNCox’s regression analysis demonstrated that renal survival time was significantly influenced byIn conclusion, the clinical characteristics of DN vary, and renal biopsy is necessary to determine renal

Keywords： diabetic nephropathy     clinical characteristics     renal biopsy     outcomes    

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Design and evaluation of a novel biopsy needle with hemostatic function

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 2, doi: 10.1007/s11465-022-0738-7

Abstract: Biopsy is a method commonly used for early cancer diagnosis.However, bleeding complications of widely available biopsy are risky for patients.Safer biopsy will result in a more accurate cancer diagnosis and a decrease in the risk of complicationsIn this article, we propose a novel biopsy needle that can reduce bleeding during biopsy procedures andThe proposed biopsy needle features a compact structure and can be operated easily by left and right

Keywords： cancer diagnosis     biopsy needle     hemostatic function     predictive model     coupled Eulerian−Lagrangian    

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Application of liquid biopsy in precision medicine: opportunities and challenges

Junyun Wang, Shuang Chang, Guochao Li, Yingli Sun

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 522-527 doi: 10.1007/s11684-017-0526-7

Abstract: circulating tumor cell (CTC) or circulating tumor DNA (ctDNA) in plasma or serum could serve as liquid biopsy

Keywords： liquid biopsy     circulating tumor cells     cell-free ctDNA     exosomes     precision medicine    

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Utility of transbronchial biopsy in the diagnosis of lymphangioleiomyomatosis

Riffat Meraj, Kathryn A. Wikenheiser-Brokamp, Lisa R. Young, Sue Byrnes, Francis X. McCormack

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 395-405 doi: 10.1007/s11684-012-0231-5

Abstract: Although surgical lung biopsy is considered the gold standard for obtaining tissue in patients with diffuseThe objective of our study was to examine the utility of transbronchial biopsy in the diagnosis of LAMTransbronchial biopsy specimens were subsequently collected and reviewed by an expert pathologist toWe found that transbronchial biopsy has a yield of approximately 60% in patients with LAM.of LAM, obviating the need for surgical lung biopsy in more than half of LAM patients.

Keywords： lymphangioleiomyomatosis     lymphangiomyomatosis     multicystic lung disease     diffuse cystic lung disease     transbronchial biopsy    

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The second short-term warm ischemia after vascular anastomosis did not affect early renal function recoveryin renal transplantation: a case report

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 329-331 doi: 10.1007/s11684-012-0211-9

Abstract: ow in the early phase of reperfusion, which has been found to be protective against renal ischemia-reperfusionWe describe a case that the allograft renal vein was twisted because of the surgeon’s mistake,

Keywords： renal transplantation     vein twist     ischemia-reperfusion injury    

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Giant renal angiomyolipoma with tuberous sclerosis complex

Ouyan SHI PhD, Guodong XU BM, Chunxiang WANG BM,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 495-498 doi: 10.1007/s11684-009-0068-8

Abstract: This article presents a case of renal AML occurring in a 14-year-old girl with a definite diagnosis ofThe pathological diagnosis was hemorrhagic renal AML.The specific risks of renal AMLs are spontaneous hemorrhage and rupture.

Keywords： renal angiomyolipoma     tuberous sclerosis complex     hemorrhage    

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Aldolase B attenuates clear cell renal cell carcinoma progression by inhibiting CtBP2

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 503-517 doi: 10.1007/s11684-022-0947-9

Abstract: Aldolase B (ALDOB), a glycolytic enzyme, is uniformly depleted in clear cell renal cell carcinoma (ccRCC

Keywords： ALDOB     kidney cancer     cell proliferation    

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Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells

Biqiong Fu, Jie Yang, Jia Chen, Lirong Lin, Kehong Chen, Weiwei Zhang, Jianguo Zhang, Yani He

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 267-276 doi: 10.1007/s11684-017-0586-8

Abstract: This study aimed to investigate the protective effect of SKI against high glucose (HG)-induced renalPrimary renal proximal tubule epithelial cells were cultured in (1) control medium (control group), mediumdown-regulation of anti-senescence molecules klotho, sirt1, and peroxisome proliferator-activated receptor- in renalSKI may be a novel strategy for protecting against HG-induced renal tubular cell senescence in treatment

Keywords： Shenkang injection     senescence     renal tubular epithelial cells     diabetic nephropathy    

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Effect of renal function and hemodialysis on the serum tumor markers in patients with chronic kidney

YU Xiaofang, XU Xialian, YE Zhibin

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 308-311 doi: 10.1007/s11684-007-0059-6

Abstract: In patients with chronic renal failure, whether they have had hemodialysis or not, the specificity ofThe effects of renal function and hemodialysis were examined on serum levels of some of the tumor markers

Keywords： CKD     non-dialysis     valuable     detection     chronic    

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Effect of pirfenidone on renal tubulointerstitial fibrosis

Dixin LI MM , Hongbing ZENG MD , Chunyang JI MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 316-322 doi: 10.1007/s11684-009-0045-2

Abstract: Renal tubulointerstitial fibrosis (TIF) is the common end stage of various chronic renal diseases, andbroad-spectrum anti-fibrotic compound but little is known about its effect and mechanism of action on renalwork, we employed a unilateral ureteral obstruction (UUO) rat model to investigate the apoptosis of renalRenal histology was studied by using periodic acid schiff reagent (PAS) and Masson trichromic stain (The content of malondialdehyde (MDA) and total activity of superoxide dismutase (T-SOD) in the renal

Keywords： pirfenidone     apoptosis     caspase 3     oxidative stress    

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Expression of renal cubilin and its potential role in tubulointerstitial inflammation induced by albumin

YANG Jurong, HE Yani, SHEN Haiying, DING Hanlu, LI Kailong, WANG Huiming

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 25-34 doi: 10.1007/s11684-008-0006-1

Abstract: Sustained proteinuria is an independent risk factor leading to kidney fibrosis and end-stage renal failure, notably albumin, has been proved to trigger interstitial inflammation and fibrosis in proteinuric renalCubilin, an endocytic receptor expressed on the renal tubular brush border, is responsible for albumingreater amount of protein in nephrotic status and albumin-induced production of MCP-1 and RANTES by renal
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Retrospective study of the efficacy and complication of thoracoabdominal incision for nephrectomy: a comparison with flank approach

Minggen YANG, Xiaokun ZHAO

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 191-196 doi: 10.1007/s11684-009-0026-5

Abstract: outcome of thoracoabdominal incision flank incision for radical nephrectomy in the patients with large renaltime, perioperative hemorrhage volume, size of tumor, success in the treatment of tumor thrombus in renalThe success rate of treating thrombus in renal vein or vena cava in group 2 was significantly higher

Keywords： surgery     renal tumors     nephrectomy    

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Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 167-172 doi: 10.1007/s11684-007-0031-5

Abstract: An independent association between acute renal failure (ARF) and intra-abdominal hypertension (IAH) afterIAH impaired renal function and was an independent risk factor for ARF after liver transplantation.
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Microbiome subsets determine tumor prognosis and molecular characteristics of clear-cell renal cell carcinoma

Frontiers of Medicine doi: 10.1007/s11684-023-1029-3

Abstract: Microbiome subsets determine tumor prognosis and molecular characteristics of clear-cell renal cell carcinoma

Keywords： tumor prognosis molecular     Microbiome subsets determine     center analysis microbiome     transcriptome data    

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Application progress of lymphography in oncology

Yang YU, Jibin LIU, Lixue YIN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 13-19 doi: 10.1007/s11684-009-0016-7

Abstract: Lymphography is often used for the diagnosis of lymphatic metastasis in oncology. Determination of lymphatic metastasis is extremely important for accurate cancer staging, which may directly guide the clinical therapeutic scheme. In recent years, the technology of lymphography has developed rapidly on the basis of traditional lymphography, with the appearance of computed tomography (CT) lymphography, nuclear magnetic resonance (MR) lymphography, contrast-enhanced lymphosonography, and so on; the diagnostic accuracy has also been improved. The imaging principles and methods of these various technologies of lymphography are reviewed in this paper, and their applications and significance in oncology are also discussed in detail.

Keywords： lymphography     lymphatic metastasis     sentinel lymph node biopsy    

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Title Author Date Type Operation

Clinical characteristics and outcomes of biopsy-proven diabetic nephropathy

Li Zhuo, Nianrong Zhang, Guming Zou, Dapeng Chen, Wenge Li

Journal Article

Design and evaluation of a novel biopsy needle with hemostatic function

Journal Article

Application of liquid biopsy in precision medicine: opportunities and challenges

Junyun Wang, Shuang Chang, Guochao Li, Yingli Sun

Journal Article

Utility of transbronchial biopsy in the diagnosis of lymphangioleiomyomatosis

Riffat Meraj, Kathryn A. Wikenheiser-Brokamp, Lisa R. Young, Sue Byrnes, Francis X. McCormack

Journal Article

The second short-term warm ischemia after vascular anastomosis did not affect early renal function recoveryin renal transplantation: a case report

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Journal Article

Giant renal angiomyolipoma with tuberous sclerosis complex

Ouyan SHI PhD, Guodong XU BM, Chunxiang WANG BM,

Journal Article

Aldolase B attenuates clear cell renal cell carcinoma progression by inhibiting CtBP2

Journal Article

Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells

Biqiong Fu, Jie Yang, Jia Chen, Lirong Lin, Kehong Chen, Weiwei Zhang, Jianguo Zhang, Yani He

Journal Article

Effect of renal function and hemodialysis on the serum tumor markers in patients with chronic kidney

YU Xiaofang, XU Xialian, YE Zhibin

Journal Article

Effect of pirfenidone on renal tubulointerstitial fibrosis

Dixin LI MM , Hongbing ZENG MD , Chunyang JI MM ,

Journal Article

Expression of renal cubilin and its potential role in tubulointerstitial inflammation induced by albumin

YANG Jurong, HE Yani, SHEN Haiying, DING Hanlu, LI Kailong, WANG Huiming

Journal Article

Retrospective study of the efficacy and complication of thoracoabdominal incision for nephrectomy: a comparison with flank approach

Minggen YANG, Xiaokun ZHAO

Journal Article

Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

Journal Article

Microbiome subsets determine tumor prognosis and molecular characteristics of clear-cell renal cell carcinoma

Journal Article

Application progress of lymphography in oncology

Yang YU, Jibin LIU, Lixue YIN

Journal Article